ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000220205 VAMP2 H. sapiens SDL Slorth 0.981985 View
ENSG00000091831 ESR1 ENSG00000213672 NCKIPSD H. sapiens SDL Slorth 0.981974 View
ENSG00000057294 PKP2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.981968 View
ENSG00000091831 ESR1 ENSG00000122692 SMU1 H. sapiens SDL Slorth 0.981934 View
ENSG00000091831 ESR1 ENSG00000161800 RACGAP1 H. sapiens SDL Slorth 0.981932 View
ENSG00000091831 ESR1 ENSG00000094631 HDAC6 H. sapiens SDL Slorth 0.981928 View
ENSG00000091831 ESR1 ENSG00000109118 PHF12 H. sapiens SDL Slorth 0.981917 View
ENSG00000091831 ESR1 ENSG00000100650 SRSF5 H. sapiens SDL Slorth 0.981911 View
ENSG00000090060 PAPOLA ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.981908 View
ENSG00000091831 ESR1 ENSG00000102471 NDFIP2 H. sapiens SDL Slorth 0.981908 View
ENSG00000091831 ESR1 ENSG00000159720 ATP6V0D1 H. sapiens SDL Slorth 0.981904 View
ENSG00000091831 ESR1 ENSG00000112144 ICK H. sapiens SDL Slorth 0.981893 View
ENSG00000091831 ESR1 ENSG00000185338 SOCS1 H. sapiens SDL Slorth 0.981861 View
ENSG00000091831 ESR1 ENSG00000115355 CCDC88A H. sapiens SDL Slorth 0.981843 View
ENSG00000091831 ESR1 ENSG00000136273 HUS1 H. sapiens SDL Slorth 0.981835 View
ENSG00000091831 ESR1 ENSG00000183765 CHEK2 H. sapiens SDL Slorth 0.981834 View
ENSG00000091831 ESR1 ENSG00000138685 FGF2 H. sapiens SDL Slorth 0.981827 View
ENSG00000091831 ESR1 ENSG00000137815 RTF1 H. sapiens SDL Slorth 0.981823 View
ENSG00000091831 ESR1 ENSG00000112081 SRSF3 H. sapiens SDL Slorth 0.98182 View
ENSG00000070808 CAMK2A ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.981795 View
ENSG00000091831 ESR1 ENSG00000205302 SNX2 H. sapiens SDL Slorth 0.981774 View
ENSG00000080561 MID2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.981755 View
ENSG00000091831 ESR1 ENSG00000204388 HSPA1B H. sapiens SDL Slorth 0.981732 View
ENSG00000072415 MPP5 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.981725 View
ENSG00000091831 ESR1 ENSG00000181090 EHMT1 H. sapiens SDL Slorth 0.981725 View
ENSG00000029363 BCLAF1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.98172 View
ENSG00000077935 SMC1B ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.981701 View
ENSG00000091831 ESR1 ENSG00000165671 NSD1 H. sapiens SDL Slorth 0.981685 View
ENSG00000091831 ESR1 ENSG00000138674 SEC31A H. sapiens SDL Slorth 0.981675 View
ENSG00000091831 ESR1 ENSG00000184840 TMED9 H. sapiens SDL Slorth 0.981675 View
ENSG00000091831 ESR1 ENSG00000136631 VPS45 H. sapiens SDL Slorth 0.981666 View
ENSG00000091831 ESR1 ENSG00000171150 SOCS5 H. sapiens SDL Slorth 0.981661 View
ENSG00000091831 ESR1 ENSG00000108654 DDX5 H. sapiens SDL Slorth 0.981644 View
ENSG00000091831 ESR1 ENSG00000143437 ARNT H. sapiens SDL Slorth 0.981612 View
ENSG00000091831 ESR1 ENSG00000127564 PKMYT1 H. sapiens SDL Slorth 0.981611 View
ENSG00000091831 ESR1 ENSG00000178999 AURKB H. sapiens SDL Slorth 0.98161 View
ENSG00000091831 ESR1 ENSG00000163624 CDS1 H. sapiens SDL Slorth 0.981594 View
ENSG00000091831 ESR1 ENSG00000123191 ATP7B H. sapiens SDL Slorth 0.981578 View
ENSG00000091831 ESR1 ENSG00000117461 PIK3R3 H. sapiens SDL Slorth 0.98156 View
ENSG00000005884 ITGA3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.981554 View